As explained in other parts of this brochure and our main website, unicellular organisms, bacteria, protozoa, and fungi, as well as cancer cells, are primitive cells which are biologically similar in many aspects. Not only do they share the same cellular origin, but they also have the same primitive cycle of life: they reproduce, invade surrounding tissues or materials in search of food, and migrate to distant organs for more space to multiply and feed, frequently resulting in disease or death of the host. The scientific details of this similarity among cells, and in particular unicellular organisms, are discussed by Dr. Arguello in his book "Atavistic Metamorphosis; A New and Logical Explanation on the Origin and Nature of Cancer" (2011).

Although unproven and totally speculative, we believe that the immune system can see and recognize molecular similarities on the surface of cancer cells, bacteria, protozoa and/or fungi. It is well known that vaccination for given bacteria can indirectly protect the individual from other types of infections for different organisms not related to those in the vaccine. This is known as cross-protective immunity or resistance to phylogenetically unrelated organisms.

It is possible that this protection generated with one vaccine, for example BCG for tuberculosis, and the resulting protection against other types of infections, including prevention of cancer development, may be due to the fact that the immune system is able to detect molecular similarities among all these unicellular organisms—molecular similarities that we have never studied before, that our laboratory tools are incapable of detecting, or that we simply do not even suspect exist.

So, our goal is to stimulate the immune system to attack dead cells of bacteria, fungi and/or protozoa, as well as the inactive toxins (toxoids) produced by some of these organisms, with the hope that such an immune attack mounted against the antigens of the above target cross-reacts against the primitive cancer cells in the body of the patient.

We do not employ living organisms or active toxins, but commercial  vaccines that include BCG (tuberculosis), Tdap (tetanus/diphtheria), PapTap (several dead bacteria and candida fungi), and under consideration are several others. Some of these vaccines can be administered to you by your family doctor.

Are You Skeptical About the Idea That Immunity Against Unicellular Organisms or Their Toxins Can Cross-React Against Cancer Cells and Kill Them? Don't Be; See Below:

(1)   For more than 100 years it has been known that complete cancer regression can occur following bacterial, fungal, viral, and protozoal infections. The most likely reason for this is that immune attacks mounted against those microorganisms cross react with cancer cells rather than those organisms killing the cancer cells themselves.

Review Published by the University of British Columbia, Vancouver and the University of Victoria, Victoria, BC, Canada.

(2)  In 1999, researchers at the University of Mississippi Medical Center in Jackson described four case studies in which the regression of malignant brain tumors co-occurred with bacterial infection. Rather than the direct action of bacteria on the tumors themselves, they concluded that microbial infections may influence immune responses in brain tumor defense.

Study reported by the Department of Neurosurgery, The University of Mississippi Medical Center, Jackson, MS, USA.

(3)  In 1982, Dr. Silvio Buzzi from Ravenna, Italy, reported partial and complete responses to diphtheria toxin (product from Corynebacterium Diphtheriae bacteria)  in 50 patients with advanced cancers that lasted up to 25 months. Dr. Arguello and Dr. Buzzi collaborated between 1994 and 1997. Dr. Buzzi's hypothesis that the antitumor response was mediated by the immune system attacking the toxin, and cross-reacting against the cancer cells, rather than the action of the toxin itself, was confirmed.

Original article by Dr. Silvio Buzzi, Cancer Res. 1982.

(4) You may know that the first line of treatment today for superficial bladder cancer is not using DNA-damaging or antiproliferative toxic drugs, but simply the instillation of the tuberculosis causing bacteria, or other forms of bacteria, into the bladder. Again, this phenomenon appears to be mediated purely by the immune system.

Review published in Nature 2013 by the Institut Pasteur, Paris, France.